Hi i'm having a ruff time in the karahanah palace the farthest i'v gotten is to the second boss in it and have lost badly i need help bad!!!
You didn't mention school and level...and if you tried it alone or not. I perfer to do it alone, especially if I am running a death or myth. I can see Storm having problems if they try it without prisms. But really, it comes down to having a small deck so you can get the spells you plan on using...all the bosses are small enough that a blade and trap combo on a 4-pip spell should hit hard enough to take out (or a 3-pip myth).
Also, refill using the healing whisps before the next battle....sometimes you have to go backwards in the dungeon a bit to find enough, but it is doable.
My suggestion: Blade, 2-pip to take out the minion, (prism,) blade, trap, 4-pip spell to take out the boss. That is six rounds, and you should take under 1000 damage.